The other Ebola debate: What about existing drugs?

first_imgAn ethical panel convened by the World Health Organization (WHO) broke new ground today when it said that using experimental, unapproved drugs or vaccines in the current Ebola outbreak is ethical—assuming a set of criteria is met. There is a big problem, however: None of the experimental therapies and vaccines appears to be available in quantities large enough to treat the thousands in need. One of the issues that needs to be debated is how to fairly distribute the scant resources, the panel said in a statement.That’s why another debate is brewing among some scientists and public health officials: What about trying existing drugs that have been approved for other diseases but that might benefit Ebola patients as well?Several researchers have floated proposals for trying such drugs. One idea—to try using statins and other widely used, cheap medicines—created a “firestorm” this past weekend after a draft op-ed piece discussing the plan (which was submitted to The New York Times today) was circulated to some 80 researchers worldwide, says Thomas Geisbert, an Ebola researcher at the University of Texas Medical Branch in Galveston.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)Geisbert is squarely opposed to the idea, because he says there isn’t enough evidence that the drugs would do any good. “I am very, very concerned about this,” he says.But David Fedson, a retired pharma executive living in France who drafted the article together with Steven Opal of Brown University, says there is enough reason to believe that statins and some other used drugs such as ACE inhibitors and angiotensin receptor blockers can save lives and should be tried. Fedson says almost 30 scientists, including very prominent ones, have agreed to co-sign the article.In Fedson’s view, the problem in Ebola is not so much the virus infection itself but a runaway immune reaction that also occurs in the bacterial infection known as sepsis. Statins and other drugs can dampen that immune reaction; a 2012 trial in sepsis patients showed that atorvastatin reduced the risk of progressing to severe sepsis by 83%. He says he has written to WHO Assistant Director-General Marie-Paule Kieny about the idea; she replied with a detailed letter about the agency’s reservations, he says. The op-ed article is another attempt to get the issue on the international agenda.But Geisbert thinks it’s a terrible idea. Researchers should be able to show that any therapy taken to Africa has at least prevented death in monkeys, he says—and the drugs that Fedson and Opal are promoting haven’t met that test. “I completely understand that people mean well, and we all want to do something,” Geisbert says. “But I have seen so many things that looked promising and didn’t work in rodents, or that worked in rodents but didn’t protect monkeys. … We shouldn’t just grab anything on the back burner” that’s approved by the U.S. Food and Drug Administration (FDA) for some uses.Compounds that change the immune response could actually make Ebola infection worse, Geisbert warns. And if drugs used today in Africa prove ineffective, that could set back the prospects of Ebola drugs as a whole, says Stephan Becker, an Ebola scientist at the University of Marburg in Germany. (Another veteran Ebola researcher at Marburg, Hans-Dieter Klenk, says he has signed the letter, however.)Fedson says that many scientists who study filoviruses like Ebola have yet to catch on to the idea of treating the immune response. “All they can think about is hammering the virus,” he says. (Fedson has also lobbied for years to get statins and other immunomodulatory agents accepted as potential treatment during influenza pandemics.)Other scientists are trying to get attention for existing drugs as well. Eleanor Fish, a researcher at the University of Toronto in Canada, is hoping to convince WHO and Doctors Without Borders of the benefits of using Infergen, a synthetic interferon α that she has studied and that has been used widely to treat hepatitis C and other diseases. Pharmunion BSV Development, the Ukrainian company that makes it, has offered to ship 60,000 vials to Africa for free, she says.Fish has long studied the broad antiviral properties of interferon α, and in 2003 she used it on patients infected with another epidemic virus, SARS; a paper she published in The Journal of the American Medical Association reported that it appeared to help them. In an e-mail she sent to officials at Doctors Without Borders and WHO yesterday, Fish cited two papers by researchers at the Public Health Agency of Canada that suggest it can help monkeys survive an otherwise fatal dose of Ebola.But in those studies, interferon—delivered by an adenovirus—was used in combination with a cocktail of monoclonal antibodies. Geisbert says the efficacy of the mix may have been due to the antibodies; past studies that he and others have conducted have found no effect on Ebola from interferon itself, he says. Fish agrees there is no published evidence that interferon by itself can save monkeys.Daniel Getts, chief scientific officer of Cour Pharma in Chicago, Illinois, says he has written WHO to suggest the use of his company’s Immune Modifying Nanoparticles, designed to reduce tissue damage by binding immune cells called monocytes. The agency has rejected the idea; “they are only interested in therapies with primate data,” he says.Some researchers also see promise in two selective estrogen receptor modulators approved by FDA—one of them is used to treat breast cancer—that were shown to inhibit Ebola infection in vitro and in a mouse model in a 2013 paper in Science Translational Medicine.Fish says she realizes she’s not the only one trying to get the agency’s attention. “I imagine people are probably falling out of the trees with all kinds of garlic therapies and who knows what,” she says. Indeed, whether WHO has time and resources to look at all of the ideas is unclear; at an 8 August press conference, WHO Director-General Margaret Chan said that her organization is “extremely stretched,” as is Doctors Without Borders. WHO’s media office did not respond to e-mails today from ScienceInsider about the topic.The outbreak shows no signs of abating. Today, WHO reported that there have been 1848 cases so far and 1013 deaths; the real numbers almost certainly exceed that tally because some patients don’t seek medical care.*The Ebola Files: Given the current Ebola outbreak, unprecedented in terms of number of people killed and rapid geographic spread, Science and Science Translational Medicine have made a collection of research and news articles on the viral disease freely available to researchers and the general public.last_img read more

Desire, heart keys in Game 2

first_imgEthel Booba on hotel’s clarification that ‘kikiam’ is ‘chicken sausage’: ‘Kung di pa pansinin, baka isipin nila ok lang’ Don’t miss out on the latest news and information. China furious as Trump signs bills in support of Hong Kong LOOK: Jane De Leon meets fellow ‘Darna’ Marian Rivera Pagasa: Storm intensifies as it nears PAR Lacson: SEA Games fund put in foundation like ‘Napoles case’ Robredo: True leaders perform well despite having ‘uninspiring’ boss PLAY LIST 02:49Robredo: True leaders perform well despite having ‘uninspiring’ boss02:42PH underwater hockey team aims to make waves in SEA Games01:44Philippines marks anniversary of massacre with calls for justice01:19Fire erupts in Barangay Tatalon in Quezon City01:07Trump talks impeachment while meeting NCAA athletes02:49World-class track facilities installed at NCC for SEA Games LATEST STORIES Aby Marano of F2 Logistics. CONTRIBUTED PHOTO, surveying the damage of Tuesday’s Finals Game 1, had a clear picture of exactly what happened: “We became too meek and lost our fire.”The feisty enforcer of F2 Logistics said her team needs to regain its confidence in order to stop Petron from sweeping the Philippine Superliga All Filipino Conference title Thursday.ADVERTISEMENT Air Force shoots down UPcenter_img Another vape smoker nabbed in Lucena MOST READ View comments Pagasa: Kammuri now a typhoon, may enter PAR by weekend “We have to come out like we are ready to eat our opponents alive,” Maraño said in Filipino. “It’s a test of character for us.”Game time is 6:30 p.m. at Filoil Flying V Centre in San Juan.FEATURED STORIESSPORTSSEA Games: Biñan football stadium stands out in preparedness, completionSPORTSPrivate companies step in to help SEA Games hostingSPORTSWin or don’t eat: the Philippines’ poverty-driven, world-beating pool starsWith a solid lineup that they use efficiently, the Blaze Spikers blasted the Cargo Movers, 25-23, 25-21, 25-19, to inch closer to their first title in two seasons.“You know our team, we have a way of coming back,” said Maraño. “We just have to erase doubts in our mind. Yes it was a three-set defeat. But we need to move on. I know we can do it as one whole team.” El Nido residents told to vacate beach homes “I know that what we showed in Game 1 wasn’t the real performance of F2 Logistics,” De Jesus said. “The adrenaline of the players in Game 1 was so high that they tend to commit mistakes.”De Jesus added: “I told them that some of them were selected in the national team, so they might as well come up with ‘national team-like’ performance.”F2 Logistics boasts national team players in Maraño, Kim Fajardo, Dawn Macandili and Kiana Dy.Petron has four in Mika Reyes, Rhea Dimaculangan, Aiza Pontillas and Ces Molina, who topscored in Game 1 with 11 points.Of the national team mainstays of F2 Logistics, top libero Macandili played below expectations, failing to get first ball which created a domino effect in their offense.But De Jesus expressed confidence on his players that include reigning UAAP champions Majoy Baron, Desiree Cheng, Macandili and Dy of La Salle.“My players are warriors,” said De Jesus, “I know they will come back and redeem themselves. It’s not over yet. The series won’t end on Thursday.”Sports Related Videospowered by AdSparcRead Next For Petron coach Shaq delos Santos, it was his wards’ burning desire to win that made the Game 1 victory possible.“It was our heart which carried us in this game,” he said. “We’re already in the championship match. It’s no longer a question of skills or talent; it’s now a question of willingness and desire. Whoever wants it more would definitely win.”But Delos Santos said they are wary F2 Logistics will come back to retain the title.“Knowing F2 (Logistics), they will surely bounce back,” he added.F2 coach Ramil de Jesus said he called for a “national team-level” performance from his wards but didn’t get one last Tuesday.ADVERTISEMENTlast_img read more

Lava launches budget Iris Atom 2 at Rs.4,949

first_imgHome grown company Lava on Tuesday launched its new budget phone, the Iris Atom 2 at Rs.4,949. The Iris Atom 2 will be available in two colours, white and black across all national retail stores, multi-brand outlets and online platforms.The Lava Iris Atom 2 has a 4.5-inch FWVGA display and is powered by a 1.3GHz quad-core processor coupled with 512MB RAM and 8GB RAM, expandable up to 32GB via microSD. The device runs Android 4.4 KitKat out-of-the-box, and is upgradable to Android 5.1 Lollipop.It sports a 5MP rear camera and a VGA front-facing camera. The phone is backed by a 1,750mAh battery.Lava recently launched the Pixel V1 Android One smartphone in India Rs.11,350. The Pixel V1 has been developed in collaboration with Google.The Pixel V1 has a 5.5-inch HD 720p display and is powered by a 1.3GHz quad-core processor with 2GB RAM and 32GB of internal memory (expandable).It comes with a 13MP rear camera along with an 8MP front-facing camera. The 3G phone is backed by a 2,560mah battery.The Android One phone runs stock Android 5.1 lollipop out-of-the-box.Lava also launched the budget Iris X1 Selfie smartphone in India recently at a price of Rs.6,777. The phone has a 4.5-inch IPS display and is powered by a 1.3GHz quad-core Mediatek MT6580 processor with 1GB of RAM and 8GB internal memory.It sports an 8MP rear camera and a 5MP front-facing camera along with LED flash.Also Read: Full review of Lava Pixel V1last_img read more

ISL 2019-20: Amine Chermiti, Amrinder Singh Heroics Give Mumbai City FC Win Over Kerala Blasters

first_imgKochi: Amine Chermiti’s 82nd minute strike saw Mumbai City FC beat Kerala Blasters FC 1-0 in a closely-fought Indian Super League clash at the Jawaharlal Nehru Stadium here on Thursday.The teams had several half-chances to break the deadlock but lacked an end product for most of the game until Chermiti’s clinical finish settled the contest. While the result meant Mumbai start their 2019-20 season with a win, it was also their first-ever win over Kerala Blasters in Kochi.Kerala Blasters struggled to test Amrinder Singh early on while Mumbai resorted to aerial balls and floating crosses into the box at the other end.A Diego Carlos cross into the box from the right flank in the 10th minute had the home defence under pressure but Mohamed Larbi’s weak header fell straight into the hands of goalkeeper Bilal Khan.Mumbai continued to threaten and Carlos outpaced Jessel Carneiro on the right flank again in the 19th minute. This time around, the former FC Pune City player attempted a powerful strike from a tight angle, forcing Bilal Khan to come up with a reflex save at his near post.OUR FIRST-EVER VICTORY IN KERALA! 😍Debutant @Chermiti9N scored the decisive goal for #ApunKaTeam to give us a fabulous opening-day victory before @Amrinder_1’s jaw-dropping save right at the end!🔵#KERMUM— Mumbai City FC (@MumbaiCityFC) October 24, 2019 At the other end, a foul by Souvik Chakrabarti allowed Sergio Cidoncha to swing a free-kick into the box from the left a few minutes later. Bartholomew Ogbeche got to the end of it at the far post but headed wide from close. The hosts had another chance at the stroke of half-time when Cidoncha whipped another one in from a similar position, but Jairo’s powerful header was saved by Amrinder Singh at the near post.Mumbai started on the front foot after the change of ends and went close in the 53rd minute. Larbi’s cross from the left found Modou Sougou unmarked in the centre of the box but the Senegalese striker’s first-time shot flew over.The game continued to swing from one half-chance to another at both ends. Minutes after the hour mark, a Cidoncha corner was headed clear by the Mumbai defence, straight to Carneiro who unleashed a thunderous, outside-the-boot strike that flew just over Amrinder’s goal.Just when it seemed like spoils would be shared in Kochi, Chermiti stunned the Kerala crowd with a late goal. Souvik Chakrabarti played a low cross into the box from the right flank which the Kerala defence failed to clear. The Tunisian striker, who was waiting in the centre, slotted the ball into the net with a fantastic first-time shot.In a last-gasp attempt to get back into the game, Ogbeche latched on to a chip by Sahal Abdul Samad inside the box but the Nigerian’s swivelling strike from close-range was miraculously saved by Amrinder as Mumbai returned home with three points. Amine ChermitiAmrinder SinghBartholomew Ogbechefootball First Published: October 24, 2019, 9:57 PM IST Get the best of News18 delivered to your inbox – subscribe to News18 Daybreak. Follow on Twitter, Instagram, Facebook, Telegram, TikTok and on YouTube, and stay in the know with what’s happening in the world around you – in real time.last_img read more

‘Rodrygo, Vini, Lucas, Bale, In That Order’: Welsh Star Booed By Real Madrid Fans

first_img Gareth Balela ligaLucas Vasquezreal madrid First Published: November 24, 2019, 5:22 PM IST Get the best of News18 delivered to your inbox – subscribe to News18 Daybreak. Follow on Twitter, Instagram, Facebook, Telegram, TikTok and on YouTube, and stay in the know with what’s happening in the world around you – in real time. Madrid: Gareth Bale was jeered loudly by the Santiago Bernabeu Stadium crowd when he went on as a late substitute in Real Madrid’s 3-1 comeback win over Real Sociedad in the Spanish league on Saturday.Madrid’s supporters expressed their anger for Bale’s peculiar celebration after helping Wales qualify for the European Championships this week. The images of Bale dancing and laughing behind a banner that read “Wales. Golf. Madrid. In That Order” were not well received in the Spanish capital. Bale was booed every time he touched the ball, including before his cross that was headed down by Karim Benzema for Luka Modric to put the result beyond doubt in the 74th minute. Afterward, Bale also received some applause for his good play.Fans in attendance had their own response to the flag that Bale carried, a poster with the message – ‘Rodrygo, Vini, Lucas, Bale, In That Order’. Photo: TwitterJust like in the pre-game news conference, coach Zinedine Zidane did not criticize Bale’s jibe at the club.”It is not for me to understand or not,” Zidane said after the game. “But we need our fans behind us for 90 minutes, as well as Gareth.”The win kept Madrid in second place, level on points with Barcelona, which leads the league on goal difference.Sociedad’s pressure led to a goal two minutes after kickoff. Willian Jose poached a poor back pass by Sergio Ramos for goalkeeper Thibaut Courtois that the Sociedad striker easily picked up and put into the empty net.Martin Odegaard, who is playing for Sociedad on loan from Madrid, along with fellow midfielder Mikel Merino and winger Mikel Oyarzabal took the initiative from the start with their passing attack that easily slipped the hosts’ attempts to press.But Madrid weathered a vibrant first half hour by Sociedad before Benzema chested in a corner kick from Modric to level in the 37th.Federico Valverde’s deflected shot put Madrid ahead two minutes into a second half that was a riveting exchange of attacking waves by both sides until Modric scored Madrid’s third goal.Sociedad, one of the league’s surprise sides, was left in fifth place at five points back.Madrid hosts Paris Saint-Germain in the Champions League on Tuesday.(With inputs from AP) last_img read more

Professional boxing hits out at move to open Games to pros

first_imgAmateur boxing’s decision to allow professionals into the Olympics for the first time drew fighting talk on Wednesday from champions and sanctioning bodies opposed to the break with tradition.The British Boxing Board of Control (BBBC), which governs the country’s professional fight scene, said the change was dangerous, disrespectful and “against the spirit of the Olympics”.”It is the hope of the British Boxing Board of Control and many within the professional Sport in Great Britain and throughout the world that AIBA reconsider such a move that is not beneficial to the sport as a whole,” it added in a statement.AIBA, the international boxing association for amateurs, earlier approved a constitutional change that would allow professionals to compete at the Rio Games in August.AIBA boss Ching-Kuo Wu told Reuters in Lausanne that the change to the AIBA constitution was approved with 95 per cent in favour – 84 of 88 voting members.It follows a decision in March to extend the scrapping of headguards in men’s amateur boxing – introduced three years ago – to the forthcoming Olympics.Some 26 Olympic spots will be up for grabs when fighters compete at a qualifying tournament in Venezuela next month.While an AIBA spokesman said the governing body was “acting for the Olympic legacy” and rejected fears that there would be a disparity between amateurs and professionals, boxers with experience of both disagreed.PROFESSIONALS vs AMATEURS”They’re two different sports. It’s like a badminton player playing tennis,” said Northern Ireland’s Carl Frampton, a former amateur who has won WBA and IBF world title belts at super-bantamweight, on Twitter.advertisement”What about the amateurs who have been dreaming of the Olympics for years, have yet to qualify, and some pro takes their spot at the last minute?”Britain’s former professional world champions Carl Froch and Ricky Hatton also criticised the change.”Goodbye amateur boxing now as far as I’m concerned. Can’t say I’m a fan of this,” said Hatton, the former world welterweight and light-welterweight world champion, on his Twitter feed.Former world heavyweight champion Mike Tyson, who as an amateur won gold at the 1981 and 1982 Junior Olympic Games, last week branded the proposal “ridiculous”.”It’s ridiculous, it’s foolish, and some of the pro fighters are going to get beat by the amateurs. It’s just going to happen, I really believe that,” the 49-year-old told Reuters.American Oscar De La Hoya, who won boxing gold at the 1992 Olympics as a lightweight, and went on to become a professional world champion, has also spoken out against opening up the Olympic tournament.”Nearly a quarter-century ago, when I was just an amateur boxer, I stood atop a podium in Barcelona and was presented with what I still consider the greatest prize of my career – the Olympic gold medal,” he wrote in the Los Angeles Times in April.”Had professionals been allowed to participate in the ring that year, I would not have made it so far.”last_img read more

PV Sindhu, Dipa Karmakar, Sakshi Malik and Jitu Rai receive Khel Ratna awards

first_imgRio Olympics Silver medallist shuttler PV Sindhu, Bronze medallist wrestler Sakshi Malik, gymnast Dipa Karmakar, and shooter Jitu Rai were today conferred the prestigious Rajiv Gandhi Khel Ratna – the country’s highest sporting honour – at the Rashtrapati Bhawan. (National Sports Awards: As it happened)President Pranab Mukherjee presented the awards amid thunderous applause at the Darbar Hall of the Rashtrapati Bhavan on the occasion of National Sports Day.For the first time in the history of National Sports Awards, four athletes were chosen for the Khel Ratna honour, owing to the three girls’ superlative show at the Rio Olympics. (National Sports Awards: Full list of awardees)In 2009, three athletes – boxers Vijender Singh and MC Mary Kom and wrestler Sushil Kumar – were given this award together.Sindhu won a historic silver in the women’s singles badminton, Sakshi won India’s first ever medal in Rio (bronze) in women’s wrestling while Dipa grabbed a piece of history for herself with a fourth-place finish in artistic gymnastics.Army marksman Jitu was always a contender after consistently producing medal-winning performances in the last two years, including gold at the Asian and Commonwealth Games along with a silver at the World Championships.The four Khel Ratnas, who were greeted with a loud round of applause when they walked up to receive their awards from President Mukherjee, received a medal, certificate and cash prize of Rs 7.5 lakh each.Also honoured were 15 Arjuna awardees who received statuettes, certificates and award money of Rs 5 lakh each.advertisementLong distance runner Lalita Babar, who finished a creditable 10th in the 3000m steeplechase in the Rio Games, boxer Shiva Thapa, only the third Indian to win a World Championships medal last year, and hockey players VR Raghunath and Rani Rampal were among those who received the Arjuna award.Cricketer Ajinkya Rahane, who was also selected for the Arjuna Award, missed out on the ceremony as he is in the United States with the Indian team for a Twenty20 series against the West Indies.Teen Javelin thrower Neeraj Chopra, the first Indian athlete to become a world champion at any level with a gold medal at the U-20 World Championship, was also among the Arjuna winners this year.Goalkeeper Subrata Paul was the lone footballer in the list of Arjuna awardees, which also included shooter Apurvi Chandela and wrestler Vinesh Phogat.Vinesh received her award while seated on wheelchair as she is recovering from a knee injury sustained in her second round bout during the Rio Games.This year’s Dronacharya Award was conferred upon six coaches, the most notable among them being Dipa’s coach Bishweshwar Nandi and India Test team captain Virat Kohli’s mentor Raj Kumar Sharma.(With PTI inputs)last_img read more

Oklahoma State Moves to No. 9 in AP Poll and No. 8 in Coaches

first_imgRANKTEAMFirst PlacePointsLast week 21WASHINGTON STATE–23320 16VIRGINIA TECH–55918 12LSU–93512 23TENNESSEE–15925 Who jumped up?The two teams from Oklahoma were among the biggest movers this week. USC also went from No. 6 to No. 4 (you know voters were dying to do this, and the Trojans beat Stanford late on Saturday). Georgia moved up two spots after beating Notre Dame and Louisville went up three. TCU went up to No. 20 from No. 23 after beating Arkansas on the road.Who dropped off?Ohio State went from No. 2 to No. 8. Penn State dropped a spot after beating Pitt 33-14. Auburn dropped a pair of slots after getting thwarted by Clemson in Death Valley.Now let’s take a look at the Coaches Poll where OSU is up to No. 8, ahead of Ohio State.Week 3 Coaches Poll Top 25 21South Florida024920 3Oklahoma013856 3CLEMSON11,3803 10Florida State09269 14Louisville065816 10WISCONSIN–9939 11FLORIDA STATE–94410 20TCU–35223 APNo. 10No. 11No. 9– RankTeamFirst placePointsLast Week 1ALABAMA581,5221 8Oklahoma State0102610 4USC–1,3246 11Louisiana State092012 19STANFORD–36414 After dropping last week in the AP Poll following their 59-24 defeat of Tulsa, Oklahoma State moved up to No. 9 after steamrolling South Alabama 44-7 on Friday night.There was movement in front of the Cowboys — namely OU going to No. 2 and Ohio State falling to No. 8 — and OSU jumped Wisconsin (which beat FAU) and Florida State (which was off).Here’s a look at the Week 2 AP PollWeek 3 AP Top 25 4Southern California013085 If you’re looking for the comments section, it has moved to our forum, The Chamber. You can go there to comment and holler about these articles, specifically in these threads. You can register for a free account right here and will need one to comment.If you’re wondering why we decided to do this, we wrote about that here. Thank you and cheers! 24Utah018223 5PENN STATE–1,2994 9Ohio State09622 17MIAMI (FL)–54216 14LOUISVILLE–65817 8OHIO STATE–1,0032 25Florida013424 6WASHINGTON–1,1247 5Penn State012564 24FLORIDA–14622 22SOUTH FLORIDA–18821 7MICHIGAN–1,1078 12Wisconsin091911 7Michigan010828 6Washington011737 13Georgia083015 ConclusionHere’s a look at where OSU has been in each poll. 25UCLA–119– 9OKLAHOMA STATE–1,00211 15Miami055117 13GEORGIA–88215 17Auburn048813 18Kansas State048719 19Stanford037214 1Alabama5814971 2Clemson213863 22Washington State024422 23Tennessee021921 18KANSAS STATE–47519 20Texas Christian027126 15AUBURN–59113 PreseasonWeek 2Week 3Week 4 2OKLAHOMA21,4475 CoachesNo. 11No. 10No. 8– 16Virginia Tech050918last_img read more

5-Star WR Clarifies Comments Trashing Georgia Coaches

first_imgGeorgia's mascot dancing on the field.ATLANTA, GA – JANUARY 08: Hairy Dawg, the mascot for the Georgia Bulldogs on the field during the first quarter against the Alabama Crimson Tide in the CFP National Championship presented by AT&T at Mercedes-Benz Stadium on January 8, 2018 in Atlanta, Georgia. (Photo by Mike Zarrilli/Getty Images)Wide receiver Jadon Haselwood has come under some heat over recent comments he made about the Georgia coaching staff’s efforts to recruit him.This past weekend, Haselwood attempted to clarify his comments, in which he implied that the Georgia coaches came across as “used car salesmen.”Taking to Twitter, Haselwood said that the Georgia coaches came across as “very fake” over the implication that they would expect loyalty and then in some cases leave to go to other schools.Haselwood did, however, double-down on his “used car salesman” line in his message.Thank you…— Jadon Haselwood ? ² (@jadon_haselwood) January 13, 2019The five-star wide receiver out of the state of Georgia ultimately committed to the Oklahoma Sooners.247Sports rated Haselwood as the No. 5 prospect in the nation, the No. 1 wide receiver in the nation, and the No. 1 prospect from the state of Georgia.The Bulldogs still have the No. 2 ranked recruiting class in the country, but trail SEC-rival Alabama for the top spot.last_img read more

Honorees Announced for 2018 World of Children Awards Ceremony and Benefit

first_imgWorld of Children, a global recognition and funding organization for individuals exclusively serving the needs of vulnerable children, revealed today its 2018 award winners.These five real-life heroes have dramatically improved the lives of at-risk children around the world through high-impact programs in the categories of education, health, humanitarianism, protection and youth helping youth. In addition to providing each Honoree with a substantial multi-year grant, World of Children will celebrate these recipients at the annual 2018 World of Children Awards Ceremony & Benefit on Thursday, November 1, 2018 at 583 Park Avenue in New York City.“We are thrilled to welcome five of the bravest and most courageous humanitarians from around the globe to our family,” said World of Children Co-Founder Harry Leibowitz. “Three of these Honorees are being recognized for their efforts in countries we have never before had the chance to serve — Afghanistan, Senegal and Bolivia — which is a testament to the reach and growth of our organization and our mission to find and fund the heroic efforts of heroes who are on the ground in some of the most vulnerable places in the world. This is an exciting year, and we look forward to celebrating each of these individuals’ achievements in New York City.The annual ceremony will also recognize New York-based Devin Beresheim (MARSH Finpro) and his wife Sarah with the World of Children Board of Governors’ Award for their unwavering dedication to the organization and elevating awareness for child advocates.Caryl Stern (President and CEO, US Fund for UNICEF), Lily Aldridge Followill (World of Children Ambassador, International Model, Child Advocate), Alina Cho (World of Children Advisory Council, CBS Sunday Morning Contributor) and Andy Adler (Sportscaster, Journalist, TV Personality) will serve as event hosts for the evening.This year’s Honorees include:2018 World of Children Education Honoree: Ehsan Mehrangais, founder of Afghanistan Demain, a non-governmental organization that provides education, school programs and rehabilitation to disadvantaged street children in three of the poorest neighborhoods in Kabul regardless of their gender or religion.2018 World of Children Health Honoree: Sandy Kemper, founder of Smiles Forever, which improves the quality of life for impoverished children in Cochabamba, Bolivia, through free preventative and restorative dentistry, and nutritional education to reduce conditions such as life-threatening abscesses, painful cavities and malnutrition.2018 World of Children Humanitarian Honoree: Phyllis Keino, founder of Lewa Children’s Home and mother to hundreds of orphans and abandoned children in Eldoret, Kenya, providing them with a safe home, medical care, a first-class education and a caring family environment.2018 World of Children Protection Honoree: Anta Mbow, founder of Empire des Enfants, a child-based shelter based in Dakar, Senegal that leads humanitarian action for children who have been exploited and are at risk of starvation, abduction, physical and sexual abuse after being forced to live on the streets.2018 World of Children Youth Honoree: Caragan Olles, co-founder of Bright Young Dyslexics, the only organization to offer funding for private tutoring and assistive technology for dyslexic students in Wisconsin, in addition to in-school programs to educate teachers and students on how to accommodate students with learning disabilities.World of Children receives thousands of nominations from around the world ever year and uses a uniquely rigorous vetting process to select Honorees, including extensive on-site investigations and an independent audit of each finalist. Recognized by the media as the “Nobel Prize for Child Advocates,” Honorees receive funding and educational support to help expand their program and ultimately impact the lives of even more children.The event’s Honorary Chairs include Faeth Bradley, Daniela Braga, Leonard Gorski, Dean M. Klisura, Rebecca Minkoff and Greg Scott. World of Children is led by Co-Founders Harry Leibowitz and Kay Isaacson-Leibowitz, retired senior executives from Procter & Gamble and Victoria’s Secret respectively.Find out more about the event here.last_img read more

King Mohammed VI to Chair Council of Ministers Thursday

Rabat – King Mohammed VI will convene Morocco’s Council of Ministers at the Royal Palace of Rabat on Thursday evening.Several laws and appointment activities are expected to take place during the meeting.The Council of Ministers will occur just a few days after the monarch’s return to Morocco following the recovery period for his heart surgery in France. King Mohammed VI’s private plane arrived in Morocco’s Mohammed V Airport in Casablanca on Monday night.The monarch successfully underwent surgery in January, following a minor arrhythmia on an otherwise healthy heart, according to a statement from the Royal Place on February 26.

At UN session Indonesian President urges new strategic mindset for global peace

“There is no question that the world we live in today is in much better condition than the one in the 20th century. Freedom has spread. The threat of nuclear holocaust is receding significantly. There is no prospect of a world war, the kind of which twice wrecked the 20th century,” President Yudhoyono told the gathered delegates at UN Headquarters in New York during the first day of the Assembly’s General Debate. “However, it is only relative peace. Not total peace as yet,” he warned, noting that the world had moved on from the Cold War to “an era of warm peace.” Underlining the concept of a “warm peace,” President Yudhoyono said that the global security architecture still reflected 20th century circumstances; that questions on how emerging powers would be accommodated by the existing world order continued to go unanswered; and, that old rivalries and long-standing conflicts – such as the Arab-Israeli conflict, disputes in the South China Sea, and tensions on the Korean Peninsula – still risked resurfacing. “The first thing we have to do is to evolve a new strategic mindset,” he stated. “The remnants of Cold War mentality still persist in parts of the geopolitical landscape – not least our own UN, where rigid, dogmatic, zero-sum calculations sometimes still come into play.”In order to usher in a new mental approach in dealing with the world’s most complex issues, President Yudhoyono stressed that Security Council reform must continue unabated until the Council reflected the 21st century strategic reality. He also urged the creation of “a universal culture of mutual tolerance and mutual appreciation” of religious differences and called for the establishment of an international body “to effectively prevent incitement to hostility or violence based on religions or beliefs.” In addition, he encouraged the doctrine of strong regionalism and pointed to the successes of the Association of Southeast Asian Nations (ASEAN) – the regional body of which Indonesia is a part. Pointing to the growing need for preventive diplomacy, President Yudhoyono argued that robust regional entities helped resolve simmering disputes before they escalated into full blown conflict and said that ASEAN had done just that in the South China Sea. “The territorial and sovereignty disputes have been festering there for the better part of a century,” he said. “But we are managing them with restraint, confidence building and, at present, through earnest negotiations toward a legally binding Code of Conduct in the South China Sea.” Scores of the world’s heads of State and government and other high-level officials are expected to present their views and comment on issues of individual national and international relevance at the Assembly’s General Debate, which ends on 1 October. read more

Violent attacks reported against civilians fleeing ISILcontrolled areas of Iraq – UN

“We have received reports that suggest a violent clampdown on people who are attempting to flee ISIL-controlled areas in Iraq, particularly through the Hamrin mountain chain in northeast Iraq” and onto Tikrit, Al-Alam and Kirkuk, said spokesperson Ravina Shamdasani of the Office of the UN High Commissioner for Human Rights (OHCHR).Ms. Shamdasani told reporters in Geneva, Switzerland, that an increasing number of people have been attempting to escape, taking a very difficult journey, and at least four families, including children and elderly people, reportedly died earlier this month after attempting the journey without a guide and with few supplies. According to sources, the journey takes eight to 12 hours in very hot weather through uninhabited areas without signage or paved roads, she said.“ISIL gunmen have also begun to set ambushes for people fleeing and ISIL snipers have reportedly attacked and killed those caught,” according to the OHCHR. “In one incident, three taxi drivers were reportedly executed between 10 and 12 July in Shirqat, purportedly for assisting residents in making the passage through Hamrin.”There are also reports that many other families were abducted by ISIL en route to Tikrit and Al-Alam, it said.“Any intentional direct attack against civilians is considered a serious violation of international humanitarian law,” the human rights spokesperson said. “All parties must ensure that civilians are protected, that they have unhindered access to medical facilities and humanitarian assistance, and that they are able to leave areas affected by violence – safely and with dignity.”Ms. Shamdasani also said “ISIL continues to viciously target those perceived to be opposed to its ideology and rule, with despicable violence.”On 20 July, for example, ISIL reportedly publicly killed an Imam in western Mosul following a decision by a self-appointed so-called court, allegedly for having criticised ISIL, and earlier this month four other Imams were allegedly executed for performing tarweed prayers, which are not authorized by ISIL.Furthermore, on 10 July, ISIL reportedly killed nine people in central Mosul by running a bulldozer over them for allegedly provided information and collaborating with the Iraqi Security Forces and Peshmerga. There have also been an increasing number of civilian casualties across the country due to car bombs and gun attacks are also occurring with frequency, according to the OHCHR. read more

Smart money moving to green financing reveals new UN report

In its new report on green finance, the UN Environment Programme (UNEP) has noted that the G20 and other countries have taken huge strides over the last year towards mobilizing public resources and private capital needed to make sustainable development and climate action a reality.“The world has committed to creating a better future for people and planet. But we will not be able to achieve [this] vision without the global financial system using its capital to fuel the transformation,” said the Executive Director of UNEP, Erik Solheim, in a news release announcing the findings. “This new research […] shows encouraging progress in this regard. From a record number of new green finance measures to ambitious plans for green finance hubs, we are seeing the smart money move to green financing,” he added. The Green Finance Progress Report further notes that the establishment of the Green Finance Study Group by the G20 last year, under its Chinese Presidency, showed the group understood that green financing at scale is critical to achieve the G20’s goal of securing balanced and sustained growth. This message was reinforced by Germany’s decision to continue the work during its G20 Presidency this year, the report highlights. The report also draws out examples from G20 countries of actions they took in relation to green finance, such as the disclosure requirements announced by the Securities and Exchange Board of India for the issuing and listing of green debt securities, and pilot areas for green finance announced by the State Council of China. It also finds that the progress made nationally, internationally, and in financial and capital markets shows that financial system is reshaping themselves to align with the sustainable development imperatives of the 21st century. “The challenge now is to rapidly increase capital flows to investments that will support our sustainable development objectives and create commercially viable green businesses for decades to come,” said Mr. Solheim. “The G20 and others have set the wheels in motion. Now is the time to press hard on the accelerator,” he added. read more

Schools in lockdown amid concerns knife attacker could still be at large

Police said initial investigations indicated he had been stabbed in the Silver Street area around three miles away but made his way to Seven Sisters before collapsing.The last incident took place on Sunday morning at 9.43am hours when a man had been stabbed in the back in Brettenham Road in Walthamstow. They are also being warned to stick to main roads rather than take shortcuts and not to listen to music or be distracted by their smartphones when walking.Police said they are looking for a tall, slim black man, possibly wearing a hooded top.Patrols have been stepped up in the area and the public have been warned to remain vigilant until the assailant is definitely caught. Four people were stabbed in Edmonton, north London The first of the linked attacks took place on Saturday evening when a 45-year-old woman was approached by a man and knifed once in the back as she walked along residential AberdeenRoad in Edmonton.Locals who heard the woman’s screams ran to her aid and tended to her until the paramedics arrived.She was taken to an east London hospital where her condition was described as critical.Around four hours later the same attacker is believed to have approached a 52-year-old man on Park Avenue in Edmonton around three miles away stabbing him more than once.The victim was taken to an east London hospital for treatment where his condition was described as not life threatening.A few hours later, just before 4am, police received reports that another person had been stabbed in the area.This time they found a 23-year-old man close to Seven Sisters Tube station suffering from knife injuries. Schools close to where a knife attacker stabbed four people during a 14 hour rampage have been placed in lockdown amid concern that he could still be at large.The attacker stabbed four people at random in the Edmonton area of north London between Saturday evening and Sunday morning.Two people, including a 45-year-old woman and a 23-year-old man, were left in a critical condition after what the police condemned as “senseless and cowardly” attacks.Two people remain in custody on suspicion of causing grievous bodily harm, but police have been unable to say whether they have apprehended the person responsible.As a result, schools in the local area have increased security and have placed their pupils on lockdown.Children at schools in Edmonton are being restricted from leaving the premises during breaks and lunchtime and are being advised to walk home in pairs or small groups. Want the best of The Telegraph direct to your email and WhatsApp? Sign up to our free twice-daily  Front Page newsletter and new  audio briefings. Four people were stabbed in Edmonton, north London Police said while the victim’s injuries were not life threatening, they were potentially life- changing.Detective Superintendent Luke Marks, from the North Area Command Unit, said: “Our investigation into these assaults is ongoing and, to date, our enquiries have resulted in two people being arrested.”All four of the victims were assaulted from behind in the street in seemingly random attacks. Due to the proximity of the assaults, we still believe that a single suspect was involved andenquiries, including the review of CCTV footage, are ongoing.”Two of the victims remain in a critical condition and a third is receiving medical treatment. We are in contact with the fourth victim who has been discharged from hospital.”I would ask that anyone with information come forward and contact us.”I am also continuing to encourage people to remain vigilant, especially when walking alone. You will see uniformed patrols in the Edmonton area; if you have any concerns, please speak with my officers.” read more

Facebook Traffic Jumps 55 Percent in a Year

first_imgIs Facebook plateauing? Hardly. The social networking giantcontinued its quest for global domination, growing 55 percent in the past year,according to comScore’s numbers. The site jumped from 97.37 million uniques in theU.S. in October2009 to 151.13 million.The social network is the number two site in the U.S.,just behind Google’s 173.3 million uniques. It boasts some 500 million membersglobally, making it second place site in the world (again, behind Google). AdChoices广告last_img

Woman sent tip to FBI last month that Florida shooting suspect is

first_img Image: Mike Stocker via PA Images By Associated Press Friday 23 Feb 2018, 10:33 PM Feb 23rd 2018, 10:33 PM Margarita Lasalle, a bookeeper and Joellen Berman, a guidance data specialist look at the memorial after returning to the school. Share66 Tweet Email Short URLcenter_img No Comments Woman sent tip to FBI last month that Florida shooting suspect ‘is going to explode’ The woman described Cruz’s short temper and said he had the “mental capacity of a 12 to 14 year old”. Margarita Lasalle, a bookeeper and Joellen Berman, a guidance data specialist look at the memorial after returning to the school. Image: Mike Stocker via PA Images A WOMAN CLOSE to the man charged with killing 17 people at a Florida high school warned the FBI he had rifles and said, “I know he is going to explode”.That’s according to a transcript of the 5 January tip to the FBI’s call centre, which was obtained today by the Associated Press.The FBI has acknowledged it failed to investigate the tip about 19-year-old Nikolas Cruz. But the transcript, first reported by The Wall Street Journal, provides new details.The woman described Cruz’s short temper and said he had the “mental capacity of a 12 to 14 year old”.She said Cruz posted pictures of weapons on social media, writing, “I want to kill people.”The woman told the FBI, “I do believe something’s going to happen”.According to the Wall Street Journal, she made the call because she wanted a “clear conscience if he takes off and, and just starts shooting places up”.Nineteen-year-old Cruz is charged with killing 17 people and wounding many others in last Wednesday’s Valentine’s Day attack at Marjory Stoneman Douglas High School, which he once attended.His lawyers have said he will plead guilty if prosecutors agree not to pursue the death penalty. No decision has been made on that.Several of the students have criticised the president, whose election was strongly supported by the National Rifle Association and who ran on a platform opposing gun control.Read: Donald Trump says armed officer who didn’t confront school shooter may be ‘a coward’Read: NRA chief criticises ‘politicisation’ of Florida school shooting 36,573 Views Tweet thisShare on FacebookEmail this articlelast_img read more

Iniesta denies interest in Man City move

first_imgAndres Iniesta has revealed that Pep Guardiola sent him messages after his announcement that he will be leaving Barcelona in the summer, but has denied any interest in joining at Manchester CityThe veteran playmaker has previously revealed that he is now close to making a final decision on his future and expects an announcement to be made soon.Iniesta is expected to join either the Chinese Super League or the J-League in the summer, but that has not stopped reports emerging that the Spaniard has been in contact with his former Barcelona boss over a move to the Premier League instead.The 34-year-old has now denied he has ever had any interest in joining City and stated that his loyalty to Barcelona means that he will never be able to allow himself to join a rival club.“Yes, Pep Guardiola has sent me messages, but reports came out that I did not understand,” said Iniesta, when asked about City (via Marca).“I will not compete against Barcelona.“My period in elite football ends with Barcelona.”norwich city, manchester city, premier leagueReport: City are stunned by Norwich George Patchias – September 14, 2019 Manchester City was stunned by Norwich City in todays Premier League clash.Much has been made in recent days of the potential impact of Aymeric…The departing midfielder is hopeful that he can return to Barcelona at some point in the future on a non-playing capacity, but for now intends to prolong his playing career.“I would love to return, this is my home,” he said. “I have grown up here since I was 12.“I would love to keep forming part of this club.“The itch to move into coaching is starting to hit me.“I will obtain a coaching badge, but I still have time left to play right now.“I don’t know how everything will be in seven years or in 10.”last_img read more

Nonprofit Just in Time helping young adults transition out of foster care

first_img Posted: May 15, 2019 00:00 00:00 spaceplay / pause qunload | stop ffullscreenshift + ←→slower / faster ↑↓volume mmute ←→seek  . seek to previous 12… 6 seek to 10%, 20% … 60% XColor SettingsAaAaAaAaTextBackgroundOpacity SettingsTextOpaqueSemi-TransparentBackgroundSemi-TransparentOpaqueTransparentFont SettingsSize||TypeSerif MonospaceSerifSans Serif MonospaceSans SerifCasualCursiveSmallCapsResetSave SettingsSAN DIEGO (KUSI) – May is National Foster Care month. And one local organization helps those who are transitioning from the foster care system to being out on their own when they become adults.The nonprofit Just in Time Foster Care helps former foster children in many ways.One program it has is called My First Home called. At its distribution center in Mission Gorge, qualifying young adults who are coming out of foster care can pick out furniture to furnish their first apartment or home.The program has proven to help former foster children to become confident capable and connected.Just in Time is always in need of more furniture if you can donate furniture or volunteer go to Updated: 6:09 AM May 15, 2019 Non-profit “Just in Time” helping young adults transition out of foster carecenter_img KUSI Newsroom, Categories: Local San Diego News FacebookTwitter KUSI Newsroom last_img read more

Party leaders clash over Obama as election nears

first_imgWASHINGTON — Claiming new momentum 48 hours before polls open across America, Republicans on Sunday assailed President Barack Obama in a final weekend push to motivate voters as Democrats deployed their biggest stars to help preserve an endangered Senate majority.GOP officials from Alaska to Georgia seized on the president’s low approval ratings, which have overshadowed an election season in which roughly 60 percent of eligible voters are expected to stay home. “This is really the last chance for America to pass judgment on the Obama administration and on its policies,” the GOP’s 2012 presidential nominee, Mitt Romney, said in a message echoed by Republicans across the country on the weekend.The president has avoided the nation’s most competitive contests in recent weeks, but encouraged Democrats to reject Republican cynicism during a Sunday appearance with Connecticut Gov. Dannel Malloy.“Despite all the cynicism America is making progress,” Obama said, imploring Democrats to vote on Tuesday. “Don’t stay home. Don’t let somebody else choose your future for you.”last_img read more